Trazodone
| obere ụdị nke | chemical compound  |
|---|---|
| nwere ojiji | medication |
| usoro kemịkalụ | C₁₉H₂₂ClN₅O |
| canonical SMILES | C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl |
| World Health Organisation international non-proprietary name | trazodone |
| medical condition treated | insomnia, neurotic disorder, anxiety, sleep-wake disorder, delirium |
| na-emekọrịta ihe n'ụzọ anụ ahụ | 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C |
| legal status (medicine) | boxed warning |
| pregnancy category | US pregnancy category C |
| subject has role | selective serotonin reuptake inhibitor, H1 antagonist, anxiolytic, second-generation antidepressive agents |
| stylized name | traZODone |
Trazodone, nke a na-ere n'okpuru ọtụtụ aha, [1] bụ ọgwụ na-egbochi ịda mbà n'obi. [2] [3][2]A na-eji ya agwọ nnukwu nsogbu ịda mbà n'obi, nsogbu nchegbu, nsogbu ihi ụra na, na ọgwụ ndị ọzọ, ịdabere na mmanya. [2] A na-aṅụ ya n'ọnụ.
Mmetụta ndị a na-ahụkarị gụnyere ọnụ nkụ, ike ọgwụgwụ, ọgbụgbọ, na isi ọwụwa. [2] Mmetụta ndị ọzọ siri ike nwere ike ịgụnye igbu onwe onye, ara, obi na-akụsi ike, na mgbatị ahụ ogologo oge. [4] Ọ bụghị ihe doro anya ma ojiji n'ime ime ma ọ bụ inye ara adịghị mma. [5][6]Ọ bụ ngwakọta phenylpiperazine nke serotonin antagonist na reuptake inhibitor (SARI) class. Trazodone nwekwara mmetụta [7]-eme ka mmadụ nọrọ jụụ.
A kwadoro Trazodone maka ọgwụgwọ na United States n'afọ 1981. [2] Ọ dị dị ka ọgwụ nkịtị. [2] [8] Ọnụ ego na United Kingdom maka NHS bụ ihe dịka £ 7.46 kwa ọnwa ka ọ na-erule afọ 2019.[9] Na United States, ọnụahịa zuru oke bụ ihe dịka US $ 4.53 kwa ọnwa ka ọ na-erule afọ 2018. [10][11] N'afọ 2017, ọ bụ ọgwụ nke iri atọ a na-edekarị na United States, nke nwere ihe karịrị nde ọgwụ iri abụọ na abụọ.
Edensibia
dezie- ↑ Trazodone (en). Drugs.com. Archived from the original on 16 September 2018. Retrieved on 9 February 2019.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Trazodone Hydrochloride. The American Society of Health-System Pharmacists. Archived from the original on 19 September 2018. Retrieved on 8 January 2018.
- ↑ Ton (15 November 2021). #302 Still awake? Trazodone for insomnia. CFPCLearn. Archived from the original on 28 March 2023. Retrieved on 14 June 2023.
- ↑ Trazodone Use During Pregnancy. Drugs.com. Archived from the original on 10 August 2019. Retrieved on 7 January 2018.
- ↑ Lemke (2008). Foye's Principles of Medicinal Chemistry (in en). Lippincott Williams & Wilkins. ISBN 9780781768795. Retrieved on 6 August 2020.
- ↑ Stahl (2008). Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (in en). Cambridge University Press. ISBN 9780521857024. Retrieved on 6 August 2020.
- ↑ (2015) British national formulary: BNF 69, 69th, British Medical Association, 257–258. ISBN 9780857111562.
- ↑ (2018) British national formulary: BNF 76, 76th, Pharmaceutical Press, 367. ISBN 9780857113382.
- ↑ NADAC as of 2018-01-03 (en). Centers for Medicare and Medicaid Services. Archived from the original on 24 June 2019. Retrieved on 7 January 2018.
- ↑ Trazodone Hydrochloride - Drug Usage Statistics. ClinCalc. Archived from the original on 11 April 2020. Retrieved on 11 April 2020.
- ↑ The Top 300 of 2020. ClinCalc. Archived from the original on 18 March 2020. Retrieved on 11 April 2020.