Trazodone
type of chemical entity
obere ụdị nkechemical compound Dezie
nwere ojijimedication Dezie
usoro kemịkalụC₁₉H₂₂ClN₅O Dezie
canonical SMILESC1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl Dezie
World Health Organisation international non-proprietary nametrazodone Dezie
medical condition treatedinsomnia, neurotic disorder, anxiety, sleep-wake disorder, Delirium Dezie
na-emekọrịta ihe n'ụzọ anụ ahụ5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C Dezie
legal status (medicine)boxed warning Dezie
pregnancy categoryUS pregnancy category C Dezie
subject has roleselective serotonin reuptake inhibitor, H1 antagonist, anxiolytic, second-generation antidepressive agents Dezie
stylized nametraZODone Dezie

Trazodone, nke a na-ere n'okpuru ọtụtụ aha, [1] bụ ọgwụ na-egbochi ịda mbà n'obi. [2] [3][2]A na-eji ya agwọ nnukwu nsogbu ịda mbà n'obi, nsogbu nchegbu, nsogbu ihi ụra na, na ọgwụ ndị ọzọ, ịdabere na mmanya. [2] A na-aṅụ ya n'ọnụ.

Mmetụta ndị a na-ahụkarị gụnyere ọnụ nkụ, ike ọgwụgwụ, ọgbụgbọ, na isi ọwụwa. [2] Mmetụta ndị ọzọ siri ike nwere ike ịgụnye igbu onwe onye, ara, obi na-akụsi ike, na mgbatị ahụ ogologo oge. [4] Ọ bụghị ihe doro anya ma ojiji n'ime ime ma ọ bụ inye ara adịghị mma. [5][6]Ọ bụ ngwakọta phenylpiperazine nke serotonin antagonist na reuptake inhibitor (SARI) class. Trazodone nwekwara mmetụta [7]-eme ka mmadụ nọrọ jụụ.

A kwadoro Trazodone maka ọgwụgwọ na United States n'afọ 1981. [2] Ọ dị dị ka ọgwụ nkịtị. [2] [8] Ọnụ ego na United Kingdom maka NHS bụ ihe dịka £ 7.46 kwa ọnwa ka ọ na-erule afọ 2019.[9] Na United States, ọnụahịa zuru oke bụ ihe dịka US $ 4.53 kwa ọnwa ka ọ na-erule afọ 2018. [10][11] N'afọ 2017, ọ bụ ọgwụ nke iri atọ a na-edekarị na United States, nke nwere ihe karịrị nde ọgwụ iri abụọ na abụọ.

Edensibia dezie

  1. Trazodone (en). Drugs.com. Archived from the original on 16 September 2018. Retrieved on 9 February 2019.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Trazodone Hydrochloride. The American Society of Health-System Pharmacists. Archived from the original on 19 September 2018. Retrieved on 8 January 2018.
  3. Ton (15 November 2021). #302 Still awake? Trazodone for insomnia. CFPCLearn. Archived from the original on 28 March 2023. Retrieved on 14 June 2023.
  4. Trazodone Use During Pregnancy. Drugs.com. Archived from the original on 10 August 2019. Retrieved on 7 January 2018.
  5. Lemke (2008). Foye's Principles of Medicinal Chemistry (in en). Lippincott Williams & Wilkins. ISBN 9780781768795. Retrieved on 6 August 2020. 
  6. Stahl (2008). Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (in en). Cambridge University Press. ISBN 9780521857024. Retrieved on 6 August 2020. 
  7. (2015) British national formulary: BNF 69, 69th, British Medical Association, 257–258. ISBN 9780857111562. 
  8. (2018) British national formulary: BNF 76, 76th, Pharmaceutical Press, 367. ISBN 9780857113382. 
  9. NADAC as of 2018-01-03 (en). Centers for Medicare and Medicaid Services. Archived from the original on 24 June 2019. Retrieved on 7 January 2018.
  10. Trazodone Hydrochloride - Drug Usage Statistics. ClinCalc. Archived from the original on 11 April 2020. Retrieved on 11 April 2020.
  11. The Top 300 of 2020. ClinCalc. Archived from the original on 18 March 2020. Retrieved on 11 April 2020.